Cancer Basic Science | Sebastian Zekihttps://www.sebastianzeki.co.uk/tag/cancer-basic-science/Cancer Basic ScienceSource Themes Academic (https://sourcethemes.com/academic/)en-usFri, 30 Jan 2026 00:00:00 +0000https://www.sebastianzeki.co.uk/images/icon_hu0b7a4cb9992c9ac0e91bd28ffd38dd00_9727_512x512_fill_lanczos_center_2.pngCancer Basic Sciencehttps://www.sebastianzeki.co.uk/tag/cancer-basic-science/Precancerous niche remodelling dictates nascent tumour persistence.https://www.sebastianzeki.co.uk/publication/orcid_precancerous-niche-remodelling-dictates-nascent-tumour-persi/Fri, 30 Jan 2026 00:00:00 +0000https://www.sebastianzeki.co.uk/publication/orcid_precancerous-niche-remodelling-dictates-nascent-tumour-persi/<div class="altmetric-embed" data-badge-type="donut" data-badge-popover="right" data-doi="10.1038/s41586-026-10157-8"></div>Low-cost and clinically applicable copy number profiling using repeat DNAhttps://www.sebastianzeki.co.uk/publication/orcid_low-cost-and-clinically-applicable-copy-number-profiling-usi/Sat, 01 Jan 2022 00:00:00 +0000https://www.sebastianzeki.co.uk/publication/orcid_low-cost-and-clinically-applicable-copy-number-profiling-usi/<div class="altmetric-embed" data-badge-type="donut" data-badge-popover="right" data-doi="10.1186/s12864-022-08681-8"></div>A biomarker panel predicts progression of Barrett's esophagus to esophageal adenocarcinomahttps://www.sebastianzeki.co.uk/publication/orcid_a-biomarker-panel-predicts-progression-of-barretts-esophagus/Tue, 01 Jan 2019 00:00:00 +0000https://www.sebastianzeki.co.uk/publication/orcid_a-biomarker-panel-predicts-progression-of-barretts-esophagus/<div class="altmetric-embed" data-badge-type="donut" data-badge-popover="right" data-doi="10.1093/dote/doy102"></div>Transcriptomic profiling reveals three molecular phenotypes of adenocarcinoma at the gastroesophageal junctionhttps://www.sebastianzeki.co.uk/publication/orcid_transcriptomic-profiling-reveals-three-molecular-phenotypes-/Tue, 01 Jan 2019 00:00:00 +0000https://www.sebastianzeki.co.uk/publication/orcid_transcriptomic-profiling-reveals-three-molecular-phenotypes-/Clonal Diaspora in Metastatic Esophageal Adenocarcinoma Describes a New Model of Cancer Progressionhttps://www.sebastianzeki.co.uk/publication/orcid_clonal-diaspora-in-metastatic-esophageal-adenocarcinoma-desc/Mon, 01 Jan 2018 00:00:00 +0000https://www.sebastianzeki.co.uk/publication/orcid_clonal-diaspora-in-metastatic-esophageal-adenocarcinoma-desc/<div class="altmetric-embed" data-badge-type="donut" data-badge-popover="right" data-doi="10.2139/ssrn.3155893"></div>A comparative analysis of whole genome sequencing of esophageal adenocarcinoma pre-and post-chemotherapyhttps://www.sebastianzeki.co.uk/publication/orcid_a-comparative-analysis-of-whole-genome-sequencing-of-esophag/Sun, 01 Jan 2017 00:00:00 +0000https://www.sebastianzeki.co.uk/publication/orcid_a-comparative-analysis-of-whole-genome-sequencing-of-esophag/Genomics of esophageal cancer and biomarkers for early detectionhttps://www.sebastianzeki.co.uk/publication/orcid_genomics-of-esophageal-cancer-and-biomarkers-for-early-detec/Fri, 01 Jan 2016 00:00:00 +0000https://www.sebastianzeki.co.uk/publication/orcid_genomics-of-esophageal-cancer-and-biomarkers-for-early-detec/<div class="altmetric-embed" data-badge-type="donut" data-badge-popover="right" data-doi="10.1007/978-3-319-41388-4_12"></div>The use of molecular markers in predicting dysplasia and guiding treatmenthttps://www.sebastianzeki.co.uk/publication/orcid_the-use-of-molecular-markers-in-predicting-dysplasia-and-gui/Thu, 01 Jan 2015 00:00:00 +0000https://www.sebastianzeki.co.uk/publication/orcid_the-use-of-molecular-markers-in-predicting-dysplasia-and-gui/<div class="altmetric-embed" data-badge-type="donut" data-badge-popover="right" data-doi="10.1016/j.bpg.2014.11.003"></div>Ordering of mutations in preinvasive disease stages of esophageal carcinogenesishttps://www.sebastianzeki.co.uk/publication/orcid_ordering-of-mutations-in-preinvasive-disease-stages-of-esoph/Wed, 01 Jan 2014 00:00:00 +0000https://www.sebastianzeki.co.uk/publication/orcid_ordering-of-mutations-in-preinvasive-disease-stages-of-esoph/<div class="altmetric-embed" data-badge-type="donut" data-badge-popover="right" data-doi="10.1038/ng.3013"></div>The stem cell organisation, and the proliferative and gene expression profile of Barrett's epithelium, replicates pyloric-type gastric glandshttps://www.sebastianzeki.co.uk/publication/orcid_the-stem-cell-organisation-and-the-proliferative-and-gene-ex/Wed, 01 Jan 2014 00:00:00 +0000https://www.sebastianzeki.co.uk/publication/orcid_the-stem-cell-organisation-and-the-proliferative-and-gene-ex/<div class="altmetric-embed" data-badge-type="donut" data-badge-popover="right" data-doi="10.1136/gutjnl-2013-306508"></div>Clonal Interactions in Barrett�s Carcinogenesis.https://www.sebastianzeki.co.uk/publication/orcid_clonal-interactions-in-barretts-carcinogenesis/Tue, 01 Jan 2013 00:00:00 +0000https://www.sebastianzeki.co.uk/publication/orcid_clonal-interactions-in-barretts-carcinogenesis/Clonal selection and persistence in dysplastic Barrett's esophagus and intramucosal cancers after failed radiofrequency ablationhttps://www.sebastianzeki.co.uk/publication/orcid_clonal-selection-and-persistence-in-dysplastic-barretts-esop/Tue, 01 Jan 2013 00:00:00 +0000https://www.sebastianzeki.co.uk/publication/orcid_clonal-selection-and-persistence-in-dysplastic-barretts-esop/<div class="altmetric-embed" data-badge-type="donut" data-badge-popover="right" data-doi="10.1038/ajg.2013.238"></div>Crypt dysplasia in Barrett's oesophagus shows clonal identity between crypt and surface cellshttps://www.sebastianzeki.co.uk/publication/orcid_crypt-dysplasia-in-barretts-oesophagus-shows-clonal-identity/Tue, 01 Jan 2013 00:00:00 +0000https://www.sebastianzeki.co.uk/publication/orcid_crypt-dysplasia-in-barretts-oesophagus-shows-clonal-identity/<div class="altmetric-embed" data-badge-type="donut" data-badge-popover="right" data-doi="10.1002/path.4211"></div>Utilizing DNA mutations to trace epithelial cell lineages in human tissueshttps://www.sebastianzeki.co.uk/publication/orcid_utilizing-dna-mutations-to-trace-epithelial-cell-lineages-in/Sun, 01 Jan 2012 00:00:00 +0000https://www.sebastianzeki.co.uk/publication/orcid_utilizing-dna-mutations-to-trace-epithelial-cell-lineages-in/<div class="altmetric-embed" data-badge-type="donut" data-badge-popover="right" data-doi="10.1007/978-1-61779-980-8_22"></div>Field cancerization in Barrett's esophagus.https://www.sebastianzeki.co.uk/publication/orcid_field-cancerization-in-barretts-esophagus/Sat, 01 Jan 2011 00:00:00 +0000https://www.sebastianzeki.co.uk/publication/orcid_field-cancerization-in-barretts-esophagus/Stem cells and their implications for colorectal cancerhttps://www.sebastianzeki.co.uk/publication/orcid_stem-cells-and-their-implications-for-colorectal-cancer/Sat, 01 Jan 2011 00:00:00 +0000https://www.sebastianzeki.co.uk/publication/orcid_stem-cells-and-their-implications-for-colorectal-cancer/<div class="altmetric-embed" data-badge-type="donut" data-badge-popover="right" data-doi="10.1038/nrgastro.2010.211"></div>