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Sebastian Zeki

Gastroenterology consultant
Guy's and St Thomas' NHS Trust
ORCID · Google Scholar · GitHub · sebastianzeki.co.uk

Biography

Dr Sebastian Zeki is a consultant gastroenterologist at St Thomas' Hospital in London. His research interests include upper gastrointestinal physiology, upper gastrointestinal cancer, natural language programming and quality metrics in endoscopy. He co-leads the Gastroenterology data sciences Institute in London.

Research & Clinical Interests

Education & Qualifications

PhD - Genomics of Barrett's related malignancyUniversity of London, 2013
Member of the Royal College of Physician2006
MSc Health InformaticsCity University, 2003
MBBS MBChir MedicineUniversity College London, 2001
MA in experimental psychologyCambridge University, 1998

Experience

Honorary Senior Clinical Lecturer Oct 2019 – Present
King's College
Research and teaching in gastroenterology data sciences.
Co-head of the Gastroenterology Data Sciences Institute Jan 2017 – Present
Guy's & St Thomas' NHS Trust
Leading the Gastroenterology Data Sciences Institute.
Honorary Senior Clinical Lecturer Jan 2017 – Present
Bart's Cancer Institute
Consultant Gastroenterologist Apr 2015 – Present
Guy's & St Thomas' NHS Trust
Clinical Lecturer Jun 2013 – Apr 2015
Cambridge University: MRC Hutchison
PhD Student Jan 2010 – Jun 2013
Queen Mary University of London
Gastroenterology Registrar Jun 2006 – Jan 2016
North West Thames Training Rotation
Postgraduate Internal Medicine Training Jun 2001 – Jun 2006
London

Grants & Funding

Can clinical decision making in Barrett's oesophagus surveillance be automated? A study using natural language processing gastrointestinal endoscopy reports Sep 2021 – Sep 2024
King's College London
Grant
Use of Machine Learning to automate decision making in Barrett's oesophagus surveillance Sep 2021 – Sep 2022
London and South East Postgraduate Medical and Dental Education
Award
Improving lesion recognition using routinely collected endoscopic and pathology data Oct 2019 – Feb 2021
Health Foundation
Grant
Clonal competition and genetic evolution of Barrett’s Oesophagus Aug 2010 – Aug 2013
British Society of Gastroenterology
Grant

Publications

Precancerous niche remodelling dictates nascent tumour persistence.
G Skrupskelyte, JE Rojo Arias, H Ajith, Y Dang, D Rossetti, S Han et al.
Springer Science and Business Media LLC. 2026
Effectiveness and safety of a haemostatic gel in the treatment of intraprocedural bleeding and prevention of delayed bleeding after advanced endoscopic resection of large and complex gastrointestinal neoplasia: a multicentre prospective observational PuraStat study
Htet, Hein Myat Thu, Subramaniam, Sharmila, Parra-Blanco, Adolfo, Saunders, Brian, Suzuki, Noriko, Haji, Amyn et al.
Frontline Gastroenterology. 2026
216 Feasibility of Routine Symptom Monitoring in Oesophago-Gastric Cancer Patients: Looking Toward Routine Postoperative Monitoring
Collum, Kerri-Louise, O’Brien, Catherine, Raj, Kathryn Fiona, Okten, Elif Ilayda, Taylor, Joanna, Evans, Orla et al.
British Journal of Surgery. 2025
ARGENT: Automatic Reference-free Evaluation for Open-Ended Text Generation without Source Inputs
Zhang, Xinyue, Zecevic, Agathe, Zeki, Sebastian, Roberts, Angus
Proceedings of the Fourth Workshop on Generation, Evaluation and Metrics (GEM$^2$). 2025
Development of a symptom response to treatment questionnaire for patients in follow-up after oesophago-gastrectomy for cancer
Chevallay, Mickael, Barman, Sowrav, Moss, Charlotte, Van Hemelrijck, Mieke, Evans, Orla, Taylor, Joanna et al.
Diseases of the Esophagus. 2025
Impact of endoscopic pyloric dilatation on symptom relief in delayed gastric emptying after esophageal resection—use of a novel symptom response questionnaire
Chevallay, Mickael, Barman, Sowrav, Moss, Charlotte, Van Hemelrijck, Mieke, Evans, Orla, Taylor, Joanna et al.
Diseases of the Esophagus. 2025
Improving Barrett’s Oesophagus Surveillance Scheduling with Large Language Models: A Structured Extraction Approach
Zhang, Xinyue, Zecevic, Agathe, Zeki, Sebastian, Roberts, Angus
Proceedings of the 24th Workshop on Biomedical Language Processing. 2025
Oesophageal Physiology Clinical Practice: A Case Study and Literature Review
Miah, Ismail, Wong, Terry, Zeki, Sebastian, Jafari, Jafar
Cureus. 2025
P100 Clinical validation of a novel automated algorithm to detect patients eligible for hepatocellular carcinoma surveillance from clinical letters
Zecevic, Agathe, Manaois, Erycar, Wong, Terry, Wang, Bo, Zeki, Sebastian
. 2025
Prehabilitation of Patients With Oesophageal Malignancy Undergoing Peri-Operative Treatment (Pre-EMPT): Outcomes From a Prospective Controlled Trial
Bott, R, Zylstra, J, Knight, W, Whyte, GP, Lane, AM, Moss, C et al.
Journal of Surgical Oncology. 2025
Validating Impedance/pH Sensors for Measuring Oesophageal Transit: A Study Based on Dysphagia and Barium Swallow
Miah, Ismail, Wong, Terry, Zeki, Sebastian, Jafari, Jafar
Sensors. 2025
Artificial Intelligence Tools for the Diagnosis of Eosinophilic Esophagitis in Adults Reporting Dysphagia: Development, External Validation, and Software Creation for Point-of-Care Use
Visaggi P, Del Corso G, Baiano Svizzero F, Ghisa M, Bardelli S, Venturini A et al.
The Journal of Allergy and Clinical Immunology: In Practice, 12(4):1008-1016.e1. 2024
Automated decision making in Barrett’s oesophagus: development and deployment of a natural language processing tool
Zecevic A, Jackson L, Zhang X, Pavlidis P, Dunn J, Trudgill N et al.
npj Digital Medicine, 7(1). 2024
Clinical Characteristics, Endoscopic Findings, and Treatment Outcomes in Lymphocytic Esophagitis Compared to Eosinophilic Esophagitis
Visaggi P, Savarino E, Del Corso G, Herlihy N, Ghisa M, Dunn JM et al.
American Journal of Gastroenterology, 120(2):469-472. 2024
Generation and Evaluation of Synthetic Endoscopy Free-Text Reports with Differential Privacy
Zecevic, A., Zhang, X., Zeki, S., Roberts, A.
BioNLP 2024 - 23rd Meeting of the ACL Special Interest Group on Biomedical Natural Language Processing, Proceedings of the Workshop and Shared Tasks
REsolution of Symptoms afTer Oesophago-gastric cancer REsection delphi (RESTOREd)—standardizing the definition, investigation and management of gastrointestinal symptoms and conditions after surgery
Byrne, Ben E, Siaw-Acheampong, Kwabena, Evans, Orla, Taylor, Joanna, Huddy, Fiona, Nilsson, Magnus et al.
British Journal of Surgery. 2024
The Multichannel Intraoesophageal Impedance Transit Concept
Miah, Ismail, Wong, Terry, Zeki, Sebastian, Jafari, Jafar
Cureus. 2024
The optimal duration of pH monitoring: testing the validity of Lyon 2.0 recommendations for wireless pH measurement
Rusu, Radu I, Fox, Mark R, Sweis, Rami, Zeki, Sebastian, Dunn, Jason M, Anggiansah, Angela et al.
Clinical Gastroenterology and Hepatology. 2024
Ambulatory pH-Impedance Findings Confirm That Grade B Esophagitis Provides Objective Diagnosis of Gastroesophageal Reflux Disease
Visaggi P, Del Corso G, Gyawali CP, Ghisa M, Baiano Svizzero F, Stefani Donati D et al.
American Journal of Gastroenterology, 118(5):794-801. 2023
Association of dynamic contrast-enhanced MRI and <sup>18</sup>F-Fluorodeoxyglucose PET/CT parameters with neoadjuvant therapy response and survival in esophagogastric cancer
Withey SJ, Owczarczyk K, Grzeda MT, Yip C, Deere H, Green M et al.
European Journal of Surgical Oncology, 49(10):106934. 2023
Extended Wireless pH Monitoring Significantly Increases Gastroesophageal Reflux Disease Diagnoses in Patients With a Normal pH Impedance Study
Zeki SS, Miah I, Visaggi P, Wolak A, deSilva M, Dunn JM et al.
Journal of Neurogastroenterology and Motility, 29(3):335-342. 2023
How achievable are STRIDE-II treatment targets in real-world practice and do they predict long-term treatment outcomes?
Meade S, Routledge E, Sharma E, Honap S, Zeki S, Ray S et al.
Frontline Gastroenterology, 14(4):312-318. 2023
Joint Entity and Relation Extraction in Medical Text
Zhang, L.X., Roberts, A., Zeki, S.
CEUR Workshop Proceedings. 2023
Metabolic tumour and nodal response to neoadjuvant chemotherapy on FDG PET-CT as a predictor of pathological response and survival in patients with oesophageal adenocarcinoma
Moore JL, Subesinghe M, Santaolalla A, Green M, Deere H, Van Hemelrijck M et al.
European Radiology, 33(5):3647-3659. 2023
Multiple staging investigations may not change management in patients with high-grade dysplasia or early esophageal adenocarcinoma
Reyhani A, Gimson E, Baker C, Kelly M, Maisey N, Meenan J et al.
Diseases of the Esophagus, 36(10). 2023
Pathologic Lymph Node Regression After Neoadjuvant Chemotherapy Predicts Recurrence and Survival in Esophageal Adenocarcinoma: A Multicenter Study in the United Kingdom
Moore JL, Green M, Santaolalla A, Deere H, Evans RP, Elshafie M et al.
Journal of Clinical Oncology, 41(28):4522-4534. 2023
Single-centre, single-blinded, randomised, parallel group, feasibility study protocol investigating if mandibular advancement device treatment for obstructive sleep apnoea can reduce nocturnal gastro-oesophageal reflux (MAD-Reflux trial)
O'Toole S, Moazzez R, Wojewodka G, Zeki S, Jafari J, Hope K et al.
BMJ Open, 13(8):e076661. 2023
Six-Food Elimination Diet Is Less Effective During Pollen Season in Adults With Eosinophilic Esophagitis Sensitized to Pollens
Visaggi P, Savarino E, Del Corso G, Hunter H, Baiano Svizzero F, Till SJ et al.
American Journal of Gastroenterology, 118(11):1957-1962. 2023
The Illustrated MRCP PACES Primer
Zeki S
. 2022
A retrospective cohort study: pre-operative oral enteral nutritional optimisation for Crohnʼs disease in a UK tertiary IBD centre
Meade S, Patel KV, Luber RP, O'Hanlon D, Caracostea A, Pavlidis P et al.
Alimentary Pharmacology &amp; Therapeutics, 56(4):646-663. 2022
Clinical Relevance of the Tumor Location-Modified Laurén Classification System for Gastric Cancer in a Western Population
Moore JL, Davies AR, Santaolalla A, Van Hemelrijck M, Maisey N, Lagergren J et al.
Annals of Surgical Oncology, 29(6):3911-3920. 2022
Effect of peri-operative chemotherapy regimen on survival in the treatment of locally advanced oesophago-gastric adenocarcinoma – A comparison of the FLOT and ‘MAGIC’ regimens
Moore JL, Kumar S, Santaolalla A, Patel PH, Kapiris M, Van Hemelrijck M et al.
European Journal of Cancer, 163:180-188. 2022
Low-cost and clinically applicable copy number profiling using repeat DNA
Abujudeh S, Zeki SS, van Lanschot MC, Pusung M, Weaver JM, Li X et al.
BMC Genomics, 23(1). 2022
Patient perspectives on key symptoms and preferences for follow-up after upper gastro-intestinal cancer surgery
Pucher PH, Coombes A, Evans O, Taylor J, Moore JL, White A et al.
Supportive Care in Cancer, 30(6):5269-5275. 2022
Positioning intestinal ultrasound in a UK tertiary centre: Significant estimated clinical role and cost savings
Luber RP, Petri B, Meade S, Honap S, Zeki S, Gecse KB et al.
Frontline Gastroenterology, 14(1):52-58. 2022
Regular feedback to individual endoscopists is associated with improved adenoma detection rate and other key performance indicators for colonoscopy
Lim S, Tritto G, Zeki S, DeMartino S
Frontline Gastroenterology, 13(6):509-516. 2022
Transition from esophagectomy to endoscopic therapy for early esophageal cancer
Dunn JM, Reyhani A, Santaolalla A, Zylstra J, Gimson E, Pennington M et al.
Diseases of the Esophagus, 35(3). 2022
Transnasal endoscopy: Moving from endoscopy to the clinical outpatient-blue sky thinking in oesophageal testing
Lim S, Haboubi HN, Anderson SHC, Dawson P, Machado AP, Mangsat E et al.
Frontline Gastroenterology, 13(e1):e65-e71. 2022
Does a high Mandard score really define a poor response to chemotherapy in oesophageal adenocarcinoma?
Knight WRC, Baker CR, Griffin N, Wulaningsih W, Kelly M, Davies AR et al.
British Journal of Cancer, 124(10):1653-1660. 2021
Initial experience in staging primary oesophageal/gastro-oesophageal cancer with 18F-FDG PET/MRI
Sharkey AR, Sah B, Withey SJ, Bhuva S, Neji R, Jeljeli S et al.
European Journal of Hybrid Imaging, 5(1). 2021
O32 Defining normal ranges for 96-hour wireless PH monitoring using healthy controls
Sebastian Zeki
. 2021
OFR-3 Extended wireless pH monitoring increases GERD diagnoses in patients with a normal pH impedance study
Sebastian Zeki
. 2021
P-OGC21 Patient perspectives on symptoms of importance and preferences for follow-up after major upper gastro-intestinal cancer surgery
Sebastian Zeki
British Journal of Surgery. 2021
P126 Phenotypic characterisation of suspected small bowel Crohn�s disease with natural language processing of MRE reports
Sebastian Zeki
. 2021
P229 A novel approach to radiotherapy targeting for oesophageal squamous-cell cancer using lugol�s-solution guided endoclip marking
Sebastian Zeki
. 2021
P230 Prevalence of cervical inlet patch in patients with and without globus
Sebastian Zeki
. 2021
P231 An evaluation of the endoscopic, pathologic and radiologic features of 225 patients with eosinophilic oesophagitis
Sebastian Zeki
. 2021
P237 Accuracy of the PPI test for reflux disease diagnosis: comparison with wireless ph study data
Sebastian Zeki
. 2021
P44 Regular individual feedback on key performance indicators improves polyp and adenoma detection in colonoscopy
Sebastian Zeki
. 2021
PMO-26 Intestinal ultrasound instead of endoscopy: large potential role and cost savings
Sebastian Zeki
. 2021
PTH-35 Out-of-hours dedicated trans-nasal endoscopy service--a model for endoscopy recovery during COVID pandemic
Sebastian Zeki
. 2021
PTH-67 Low rate of post-fundoplication dysphagia in patients with pre-operative oesophageal aperistalsis
Sebastian Zeki
. 2021
PTH-68 Schatzki rings are commonly misdiagnosed in patients with eosinophilic oesophagitis
Sebastian Zeki
. 2021
PTH-69 Short segment non dysplastic Barrett’s is often surveyed too early by non-experts
Sebastian Zeki
. 2021
PTH-76 Use of orodispersible budesonide in the treatment of eosinophilic oesophagitis: a single-centre audit
Sebastian Zeki
. 2021
PTU-4 Prospective validation of the edinburgh dysphagia score in South-east London
Sebastian Zeki
. 2021
Validation of the Lyon classification for GORD diagnosis: Acid exposure time assessed by prolonged wireless pH monitoring in healthy controls and patients with erosive oesophagitis
Rusu R, Fox MR, Tucker E, Zeki S, Dunn JM, Jafari J et al.
Gut, 70(12):2230-2237. 2021
Adjuvant therapy following oesophagectomy for adenocarcinoma in patients with a positive resection margin
Bott, R.K., Beckmann, K., Zylstra, J., Wilkinson, M.J., Knight, W.R.C., Baker, C.R. et al.
British Journal of Surgery. 2020
Machine learning to predict early recurrence after oesophageal cancer surgery
Rahman SA, Walker RC, Lloyd MA, Grace BL, van Boxel GI, Kingma BF et al.
British Journal of Surgery, 107(8):1042-1052. 2020
The effects of COVID-19 on IBD prescribing and service provision in a UK tertiary centre
Sebastian Zeki
GastroHep. 2020
A biomarker panel predicts progression of Barrett's esophagus to esophageal adenocarcinoma
Duits LC, Lao-Sirieix P, Wolf WA, O’Donovan M, Galeano-Dalmau N, Meijer SL et al.
Diseases of the Esophagus, 32(1). 2019
O26 QUALITY OF LIFE FOR ACHALASIA PATIENTS IS THE SAME AFTER PER-ORAL ENDOSCOPIC MYOTOMY (POEM) AND HELLER MYOTOMY
Sebastian Zeki
Diseases of the Esophagus. 2019
OTH-07 Identification of IBD cohorts from linked endoscopy and histology reports using natural language processing
Sebastian Zeki
Gut. 2019
P27 PERORAL ENDOSCOPIC MYOTOMY (POEM) FOR TREATMENT OF ACHALASIA. CLINICAL OUTCOMES OF A SINGLE-CENTER INSTITUTE IN UK
Sebastian Zeki
Diseases of the Esophagus. 2019
Prediction of a positive circumferential resection margin at surgery following neoadjuvant chemotherapy for adenocarcinoma of the oesophagus
Knight WRC, Yip C, Wulaningsih W, Jacques A, Griffin N, Zylstra J et al.
BJS Open, 3(6):767-776. 2019
PTU-047 POEM compares favorably with laparoscopic hellers myotomy as treatment for achalasia
Sebastian Zeki
. 2019
PTU-105 Automated, algorithm based extraction of Barrett�s surveillance metrics from natural language text is reliable
Sebastian Zeki
Gut. 2019
Su1136--Can Peroral Endoscopic Myotomy (POEM) Become the Treatment of Choice for Achalasia? Results of a Singlecenter Institute in UK
Sebastian Zeki
Gastroenterology. 2019
Transcriptomic profiling reveals three molecular phenotypes of adenocarcinoma at the gastroesophageal junction
Sebastian Zeki
International journal of cancer. 2019
EndoMineR for the extraction of endoscopic and associated pathology data from medical reports
S Zeki S
Journal of Open Source Software, 3(24):701. 2018
Clonal Diaspora in Metastatic Esophageal Adenocarcinoma Describes a New Model of Cancer Progression
Noorani A, Goddard M, Crawte J, Alexandrov LB, Secrier M, Eldridge MD et al.
SSRN Electronic Journal. 2018
Endoscopic management of dysplasia and early oesophageal cancer
Zeki S, Bergman J, Dunn J
Best Practice &amp; Research Clinical Gastroenterology, 36-37:27-36. 2018
Lymph node regression and survival following neoadjuvant chemotherapy in oesophageal adenocarcinoma
Davies AR, Myoteri D, Zylstra J, Baker CR, Wulaningsih W, Van Hemelrijck M et al.
British Journal of Surgery, 105(12):1639-1649. 2018
Multidisciplinary approach to the management of adult eosinophilic oesophagitis in the United Kingdom
Hunter H, Pupinyte K, Wong T, Zeki S, Dunn JM, Toner E et al.
Clinical &amp; Experimental Allergy, 48(12):1752-1756. 2018
OTU-013 Outcomes of 360 HALO express radio-frequency ablation for barrett�s oesophagus related neoplasia
Sebastian Zeki
. 2018
OWE-031 Oesophageal aperistalsis is under investigated in those without achalasia or reflux
Sebastian Zeki
. 2018
PTH-024 Risk factors for bleeding during endoscopic resection for visible lesions in barrett�s oeosphagus
Sebastian Zeki
. 2018
PTH-128 Bravo wireless PH monitoring can save time when investigating patients with eosinophilic oesophagitis
Sebastian Zeki
. 2018
PTU-144 Removal of normal and negative phrases from endoscopic semi-structured text for accurate automated endoscopic audit
Sebastian Zeki
. 2018
Tu1124-Risk Factors for Bleeding During Endoscopic Resection for Visible Lesions in Barrett's Esophagus
Sebastian Zeki
Gastroenterology. 2018
A comparative analysis of whole genome sequencing of esophageal adenocarcinoma pre-and post-chemotherapy
Sebastian Zeki
Genome research. 2017
Experienced endoscopists improve Barrett's surveillance outcomes independently of time allocation Reply
Sebastian Zeki
ENDOSCOPY. 2017
Reply to Westerveld et aland Schembri et al.
Zeki S, Ooi J, Wilson P, Walker G, Blaker P, DeMartino S et al.
Endoscopy, 49(11):1115-1115. 2017
Uvular necrosis following diagnostic gastroscopy
Digby-Bell J, Zeki S
BMJ Case Reports, 2017:bcr-2017-221959
Genomics of esophageal cancer and biomarkers for early detection
Pusung M, Zeki S, Fitzgerald R
Advances in Experimental Medicine and Biology. 2016
54 evaluation of a minimally-invasive cytosponge esophageal cell collection system in patients with Barrett's esophagus
Sebastian Zeki
Gastroenterology. 2015
The use of molecular markers in predicting dysplasia and guiding treatment
Zeki S, Fitzgerald RC
Best Practice &amp; Research Clinical Gastroenterology, 29(1):113-124. 2015
Ordering of mutations in preinvasive disease stages of esophageal carcinogenesis
Weaver JMJ, Ross-Innes CS, Shannon N, Lynch AG, Forshew T, Barbera M et al.
Nature Genetics, 46(8):837-843. 2014
Squamous cell carcinoma after radiofrequency ablation for Barrett's dysplasia
Zeki SS
World Journal of Gastroenterology, 20(15):4453. 2014
Targeting care in Barrett's oesophagus
Zeki S, Fitzgerald RC
Clinical Medicine, 14(6):s78-s83. 2014
The stem cell organisation, and the proliferative and gene expression profile of Barrett's epithelium, replicates pyloric-type gastric glands
Lavery DL, Nicholson AM, Poulsom R, Jeffery R, Hussain A, Gay LJ et al.
Gut, 63(12):1854-1863. 2014
Clonal Interactions in Barrett�s Carcinogenesis.
Sebastian Zeki
. 2013
Clonal selection and persistence in dysplastic Barrett's esophagus and intramucosal cancers after failed radiofrequency ablation
Zeki SS, Haidry R, Graham TA, Rodriguez-Justo M, Novelli M, Hoare J et al.
American Journal of Gastroenterology, 108(10):1584-1592. 2013
Crypt dysplasia in Barrett's oesophagus shows clonal identity between crypt and surface cells
Khan S, McDonald SA, Wright NA, Graham TA, Odze RD, Rodriguez‐Justo M et al.
The Journal of Pathology, 231(1):98-104. 2013
Mo1859 Senescent Barrett's Epithelium Causes Proliferation of Neighbouring Non Senescent Epithelium by Paracrine Signalling
Sebastian Zeki
Gastroenterology. 2013
Mo1623 Barretts Related Adenocarcinomas Arise as a Monoclonal Outgrowth From Polyclonal Dysplasia
Sebastian Zeki
Gastroenterology. 2012
Reply - Refeeding hypophosphataemia in patients with malnutrition: Prevention and treatment
Zeki S, Nightingale JM
Clinical Nutrition, 31(3):430. 2012
Tu1116 Recurrence After Radiofrequency Ablation for Barretts Related High Grade Dysplasia is Due to Persistence of Epithelial Mutations
Sebastian Zeki
Gastroenterology. 2012
Utilizing DNA mutations to trace epithelial cell lineages in human tissues
Zeki S, Graham TA, McDonald SAC
Methods in Molecular Biology. 2012
Field cancerization in Barrett's esophagus.
Zeki, S.S., McDonald, S.A., Graham, T.A.
Discovery medicine. 2011
Refeeding hypophosphataemia is more common in enteral than parenteral feeding in adult in patients
Zeki S, Culkin A, Gabe SM, Nightingale JM
Clinical Nutrition, 30(3):365-368. 2011
Stem cells and their implications for colorectal cancer
Zeki SS, Graham TA, Wright NA
Nature Reviews Gastroenterology &amp; Hepatology, 8(2):90-100. 2011
A deceptive magnetic resonance cholangiopancreatogram?
Sebastian Zeki
Grand Rounds. 2010
T1322 Colectomy Rates for Patients Treated for CMV Disease in the Context of Ulcerative Colitis do Not Differ From Those Who are Not Treated for CMV Disease
Sebastian Zeki
Gastroenterology. 2010
An obstructing mass in a young ulcerative colitis patient
Zeki S, Catnach S, King A, Hallan R
World Journal of Gastroenterology, 15(7):877. 2009
Characterization of inflammatory bowel disease with urinary metabolic profiling
Williams HRT, Cox IJ, Walker DG, North BV, Patel VM, Marshall SE et al.
The American Journal of Gastroenterology, 104(6):1435-1444. 2009
Erratum: Characterization of inflammatory bowel disease with urinary metabolic profiling (American Journal of Gastroenterology (2009) 104 (1435-1444) DOI: 10.1038 / ajg.2009.175)
Williams HRT, Cox IJ, Walker DG, North BV, Patel VM, Marshall SE et al.
The American Journal of Gastroenterology, 104(7):1894-1894. 2009
Risk factors for severe disease in adults with falciparum malaria
Phillips A, Bassett P, Zeki S, Newman S, Pasvol G
Clinical Infectious Diseases, 48(7):871-878. 2009
S1180 Crohn's Disease Is Associated with a Specific Urinary Metabolic Profile
Sebastian Zeki
Gastroenterology. 2008

Talks & Presentations

IBS for general practice- how to approach, how to help and how to treat Jun 2030
Natural language processing of endoscopic and pathological text Jun 2030

Educational RoleI contribute across the KCL–GSTT academic pathway: undergraduate, postgraduate, and faculty development.

## Undergraduate (KCL MBBS).

  • Gastroenterology Small-Group Teaching Block (2016 to present),
  • Delivering teaching bedside and through lectures ~25 students annually.
  • Supervisor for scholarly project module 2025/6 Shan Lee “Is severe ineffective oesophageal motility at high resolution manometry related to gastro oesophageal reflux disease on impedance testing” Pierfrancesco Visaggi (June 2018 67(Suppl 1):A210.1-A210 DOI:10.1136/gutjnl-2018-BSGAbstracts.419 : “Oesophageal aperistalsis is under investigated in those without achalasia or reflux“ - oral presentation at British Society of Gastroenterology

## Postgraduate:

  • Created innovative single subject per page online learning materials (www.gastroenteroloybook.com) with interactive multiple choice questions to improve Specialty Certificate Examination performance.
  • Publication of MRCP book (Zeki S. The Illustrated MRCP PACES Primer. Abingdon: Radcliffe Publishing; 2009. doi:10.1201/9780429091254) to help OSCE preparation for exams
  • Development of gastroenterology data science online teaching materials including full code examples to help manipulate large data sets using R (https://sebastiz.github.io/gastrodatascience//index.html)
  • Endoscopy trainer
  • Educational Supervisor Guy’s and St Thomas’ NHS Trust.

## Supervision & mentoring.

  • Primary/secondary supervisor for 2 PhD candidates (topics: NLP for endoscopy):
  • One PhD completion to date: Zhang X. Automating Surveillance Timing for Barrett’s Oesophagus: An Information Extraction Approach Using Natural Language Processing [Doctoral thesis]. London: King’s College London; 2026.
  • Current primary PhD Supervisor for a second PhD : PhD supervision via the DRIVE Health programme (Agathe Zecevic “Development and deployment of a single unified natural language model for the supervised and automated prediction of follow up for precancerous GI conditions.”) (DRIVE- Health Programme)- Topol Digital Fellow

## Educational innovation.

  • Designed an “Introduction to Clinical NLP for Gastroenterologists” workshop (hands-on notebooks using de-identified endoscopy text) now adopted by <N> deanery study days; satisfaction 4.<x>/5.
  • Website for NLP in gastroenterology

## Training & standards.

  • JAG trainer and DOPS assessor;
  • Performance optimisation done with EndoMineR.
  • Contribution to Nocgca submission as national audit.
  • Development of automated adenoma detection rates for colonoscopy with demonstration (Regular feedback to individual endoscopists is associated with improved adenoma detection rate and other key performance indicators for colonoscopy.Lim S, Tritto G, Zeki S, DeMartino S.Frontline Gastroenterol. 2022 May 6;13(6):509-516. doi: 10.1136/flgastro-2022-102091. eCollection 2022)
Generated 20 May 2026 · Auto-updated from ORCID